The Oklahoma Animal Disease Diagnostic Laboratory at Oklahoma State University is a vital facility dedicated to promoting animal health through veterinary diagnostic testing, instruction of professional students and research on diseases of economic importance to Oklahoma and beyond. Established in 1975, OADDL provides a wide range of diagnostic services, including necropsy, biopsy, bacteriology, mycology, parasite screening, serology and molecular diagnostics. The lab handles approximately 185,000 testing requests annually from 44 states, significantly expanding its services since its inception. OADDL also plays a crucial role in the One Health initiative, fostering collaborations with various departments and external partners to address complex health challenges at the intersection of animal and human health.