Running east-west along the north side of campus, Tyler Mall originates at Forest Mall on the west end and McAllister Avenue on the east end, where it continues as Tyler Street.
Tyler Mall is home to the Lyceum Theatre, Carrie Matthews Hall, A. J. Matthews Center, School of Human Evolution and Social Change, G. Homer Durham Languages and Literatures, Social Sciences, Old Main, Life Sciences C Wing, Life Sciences, Virginia G. Piper Writers House, Engineering Center G-Wing, Physical Sciences A-Wing (Wexler Hall) and F-Wing, Engineering Research Center, ISTB V, Noble Science Library, Goldwater Center, Psychology and Psychology North.